Sergio’s project

Sergio is student of the career ‘Engineering in Bioinformatics’. He is making the project ‘Search for selective trandolaprilat-derived angiotensin converting enzyme (ACE) inhibitors by using de novo design’. In this project, he has to design novel trandolaprilat derivatives by using de novo design and he has to explore the stability of the novel ligands inside the ACE binding site by using Molecular Dynamics and MM/GBSA calculations.