Insitute of Chemistry, University of Talca, Campus Lircay

Contact Information


Luis Prent Peñaloza

PHD Student (2014-2020)

University of Talca, Institute of Chemistry

Luis’ project

Luis was student of the PhD program in Applied Sciences. He made the project ‘Design, multicomponent synthesis and biological evaluation of new peptide-mimetic derivatives against the active site of each domain of angiotensin-converting enzyme I’. In this project he designed novel compounds (under a scheme of multicomponent Ugi reactions) by using the structural information of the binding sites of N domain and C domain angiotensin converting enzyme (ACE). He synthesized these compounds in the lab, and he determined their activities. His purpose was the discovery of selective ACE inhibitors.

PhD in Applied Sciences