Luis Prent Peñaloza
PHD Student (2014-...)
University of Talca, Institute of Chemistry
Luis is student of the PhD program in Applied Sciences. He is making the project ‘Design, multicomponent synthesis and biological evaluation of new peptide-mimetic derivatives against the active site of each domain of angiotensin-converting enzyme I’. In this project he is designing novel compounds (under a scheme of multicomponent Ugi reactions) by using the structural information of the binding sites of N domain and C domain angiotensin converting enzyme (ACE). He is synthesizing these compounds in the lab, and he is determining their activities. His purpose is the discovery of selective ACE inhibitors.