Luis’ project

Luis is student of the PhD program in Applied Sciences. He is making the project ‘Design, multicomponent synthesis and biological evaluation of new peptide-mimetic derivatives against the active site of each domain of angiotensin-converting enzyme I’. In this project he is designing novel compounds (under a scheme of multicomponent Ugi reactions) by using the structural information of the binding sites of N domain and C domain angiotensin converting enzyme (ACE). He is synthesizing these compounds in the lab, and he is determining their activities. His purpose is the discovery of selective ACE inhibitors.

PhD in Applied Sciences